Preventive Treatment for Immunocompromised Individuals

COVID-19 Pre-Exposure Prevention Treatment for People with Weakened Immune System to Avoid a COVID-19 Infection (Evusheld)

Desert Oasis Healthcare (DOHC) is committed to improving our communities’ access to COVID- 19 vaccines and therapeutics. In addition to providing COVID-19 vaccines, as well as IV monoclonal antibodies and oral antivirals to treat COVID-19, DOHC is an approved Riverside County regional provider of Evusheld.

Evusheld (tixagevimab and cilgavimab) is authorized under an Emergency Use Authorization (EUA) for the pre-exposure prophylaxis of COVID-19 in adults and pediatric individuals (12 years of age and older weighing at least 40 kg). What does this mean? This medication is given before an infection or exposure to avoid a COVID-19 infection for those individuals:

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  • Who are not currently infected with SARS-CoV-2 and who have not had a known recent exposure to an individual infected with SARS-CoV-2 and
  • Who have moderate to severe immune compromise due to a medical condition or receipt of immunosuppressive medications or treatments and may not mount an adequate immune response to COVID-19 vaccination or
  • For whom vaccination with any available COVID-19 vaccine, according to the approved or authorized schedule, is not recommended due to a history of severe adverse reaction (e.g., severe allergic reaction) to a COVID-19 vaccine(s) and/or COVID-19 vaccine component(s).
**Note: Evusheld is not a treatment for a COVID-19 infection, nor is it used for post-exposure prophylaxis. It is also not a replacement for vaccination.**

Who, Where, How & Cost

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Who is able to get Evusheld: Anyone who meets the medical criteria outlined above may be eligible for the prevention treatment. YOU DO NOT HAVE TO BE A DOHC MEMBER.

Where: DOHC will initially be administering Evusheld in our existing COVID-19 vaccine clinics in Indio and Palm Springs.

How: Administration involves two Intramuscular (IM) injections at the same visit every 6 months. Recipients must wait 2 weeks after their most recent COVID-19 vaccination to receive injections and should complete their primary 3 dose series of Pfizer or Moderna or complete Janssen (J&J) primary series in addition to their booster prior to receiving Evusheld. Patients should bring their vaccine cards or electronic proof of vaccination.

Cost: There is no cost to the patient, but we request they bring their insurance cards for billing purposes.


If you have any questions about Evusheld treatment or to request an appointment please call 760-969-6555 and ask about EVUSHELD. Someone on our team will assist you.

COVID-19 Symptoms?

If you are experiencing COVID-19 symptoms, take a home test if available. Otherwise, please visit one of our COVID-19 Testing & Treatment Centers.

Monday-Friday: 8:00am-4:00pm
Weekends: Please visit Immediate Care locations in Palm Springs, Yucca Valley or Indio from 9am-7pm or call the 24/7 Patient Helpline 760-969-6555.

COVID-19 Vaccine Clinics

  • Palm Springs
    275 N El Cielo, Suite D415
    Palm Springs, CA 92260
    Mon-Friday | 8am-4:30pm*
  • Indio
    81880 Dr. Carreon Blvd, Second Floor
    Indio, CA 92201
    Mon-Friday | 8am-4:30pm*
  • Yucca Valley
    57463 29 Palms Hwy, Suite 203
    Yucca Valley, CA 92284
    Tuesday & Thursdays only | 8:30am-4:30pm*

    * Closed for lunch 12-1pm

Need help scheduling?
Call 760-808-8400.
Walk-ins always accepted.

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